The gut microbiome and heart failure: A better gut for a better heart

Despite the development of new drugs and therapeutic strategies, mortality and morbidity related to heart failure (HF) remainshigh. It is also the leading cause of global mortality. Several concepts have been proposed to explore the underlying pathogenesisof HF, but there is still a strong need for more specific and complementary therapeutic options. In recent years, accumulatingevidence has demonstrated that changes in the composition of gut microbiota, referred to as dysbiosis, might play a pivotal role inthe development of several diseases, including HF.