The role of short-chain fatty acids from gut microbiota in gut-brain communication

Short-chain fatty acids(SCFAs), the main metabolites produced in the colon by bacterial fermentation of dietaryfibers and resistant starch, are speculated to play a key rolein neuro-immunoendocrineregulation. However, the underlying mechanisms through which SCFAs might influencebrain physiology and behavior have not been fully elucidated.