Gut Check

Doctors & Partners

About Our Doctors

AMILI is supported by a team of accomplished doctors with years of experience in everything related to the gut microbiome.

From certified gastroenterologists to public health specialists, our team comprises of doctors who are masters of their field. Most importantly, Dr David Ong, a member of our co-founding team, performed the first ever Faecal Microbiome Transplant (FMT) in Singapore in 2014.

Our Services

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FMT (Stool) Bank

AMILI set up Southeast Asia's first stool bank for FMT in early 2020. Since then we have provided microbiome material to hospitals and doctors in the region. Our donor selection is a stringent process in line with the current global standards.

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FMT Pills

FMT is conducted via colonoscopic insertions. However, we are in the final stages of development for Oral FMT capsules, also known as FMT Pills. Microbiome material is processed and encapsulated in a time-release double capsule that dissolves at the right location to release the microbiome material, bypassing the need for an invasive colonoscopy.

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Advisory Services

AMILI is proud to offer its unique platform and microbiome expertise to validate the impact of food and ingredients on human health. Leveraging our scientific skill and localized database, we have partnered with MNCs, CPG companies and emerging brands in product development, marketing strategy and more.

Diet, Microbiome, and Cancer Immunotherapy—A Comprehensive Review

This review shows that specific dietary patterns (such as, e.g., animal-based, vegetarian, or Mediterranean diet) alter the gut microbiome’s composition. An appropriate intestinal microbiota structure might modulate the function of human immune system, which affects the bodily anti-cancer response. This paper shows also that specific bacteria species inhabiting the gastrointestinal tract can have a beneficial influence on the efficacy of immunotherapy. Antibiotics weaken gut bacteria and worsen the immune checkpoint blockers’ efficacy, whereas a faecal microbiota transplant or probiotics supplementation may help restore bacterial balance in the intestine. Other factors (like vitamins, glucose, or BMI) change the cancer treatment response, as well. This review demonstrates that there is a strong association between one’s diet, gut microbiome composition, and the outcome of immunotherapy. However, further investigation on this subject is required.

Microbial Influences in Inflammatory Bowel Diseases

Clinical, experimental, and therapeutic studies suggest an important role for microbial agents in Crohn’s disease and pouchitis pathogenesis. Bar-nich and Darfeuille-Michaud described adherent/invasive E. coli (AIEC) that persist within epithelial cells and macrophages and selectively colonize the ileum of Crohn’s disease patients.

The role of gut microbiota in immune homeostasis and autoimmunity

Keeping a delicate balance in the immune system by eliminat-ing invading pathogens, while still maintaining self-toleranceto avoid autoimmunity, is critical for the body’s health. The gutmicrobiota that resides in the gastrointestinal tract providesessential health benefits to its host, particularly by regulatingimmune homeostasis

The gut microbiome in health and in disease

There is a fast growing collection of data describing the structure and functional capacity of themicrobiome in a variety of conditions available to the research community for consideration and furtherexploration. Ongoing efforts to further characterize the functions of the microbiome and the mechanismsunderlying host–microbe interactions will provide a better understanding of the role of the microbiome inhealth and disease.

Gut microbiota and metabolic syndrome

Metabolic syndrome (MetS) describes a set of risk factors that can eventually lead to the occurrence of cardiovascular andcerebrovascular disease. A detailed understanding of the MetS mechanism will be helpful in developing effective preventionstrategies and appropriate intervention tools.

Contact Us

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AMILI Hotline: +65 6977 7199
Email: doctors@amili.asia (Our doctors)
email: hello@amili.asia (General Queries)

Address:
89 Science Park Drive #03-09, The Rutherford, Singapore Science Park I, S118261