Project Scratch: Unlocking the Gut-Skin Axis

What if the key to healthier skin lies beyond the skin itself?

Project Scratch is an innovative research collaboration between AMILI and Sequential Skin Ltd (UK), bringing together expertise in gut, skin, and oral microbiome science to better understand inflammatory skin conditions such as eczema.

Using advanced DNA sequencing technologies, we're exploring how microbes across different parts of the body work together to influence inflammation, immunity, and skin health. By uncovering these microbial connections, we aim to develop a next-generation, at-home microbiome test that provides deeper, more personalized insights than conventional skin assessments.

Supported by a $1.8 million UK-Singapore Collaborative R&D Grant from Innovate UK and Enterprise Singapore, this research has the potential to transform how inflammatory skin disorders are understood, monitored, and managed.

Why does this matter?

Inflammatory skin disorders affect up to one in four people worldwide. Yet many diagnostic approaches focus only on the skin, overlooking the powerful connections between the gut, oral cavity, and skin microbiomes.

Project Scratch seeks to build one of the first integrated microbiome datasets across these body sites, paving the way for more personalized skincare, earlier intervention strategies, and microbiome-based solutions for long-term skin health.

Join the Study

We are recruiting 300 participants across Singapore, including healthy adults and individuals with mild-to-moderate eczema.

Participation is simple and entirely home-based:

• Collect stool, saliva, and skin swab samples using our at-home collection kits.
• Complete brief questionnaires about your health, diet, and lifestyle.
• Receive a free personalised gut & skin microbiome report for your participation.

No clinic visits required!

Complete the pre-screener today to find out if you're eligible to participate: https://tinyurl.com/ProjectScratch2026